Bee Propolis Capsules

Bee Propolis Capsules

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Uses and benefits

  • Source of naturally occurring vitamins, minerals, flavonoids, and B vitamins
  • Enhances immune function
  • Soothes sore throat when used as a mouthwash  

Feature summary

Natural Factors Bee Propolis is a nutrient-rich extract with a high concentration of antioxidants. Its antibacterial properties, ability to relieve minor inflammations, and support for immune health provides a natural form of protection in our uncertain age of superbugs, increased pollution, environmental degradation, and compromised health.

Propolis is a type of antimicrobial glue that bees make from the resins of trees. It is rich in nutrients, such as magnesium, calcium, phosphorus, potassium, beta-carotene, bioflavonoids, and vitamins B1 and B2. It is also a concentrated source of antioxidants called bioflavonoids, which are known for strengthening capillary walls and connective tissue, and enhancing vitamin C absorption. It is traditionally used in herbal medicine to help relieve minor inflammations and lesions on mucous membranes, such as canker sores.

Propolis is a very safe ingredient with no side effects or interactions. Unlike many antibiotics, it does not destroy the good bacteria living in the digestive tract.

Natural Factors Bee Propolis is part of the Enriching Bee Factors® series. It comes from the northern apiaries where trees produce the highest quality resins. Every 500 mg capsule contains a 2:1 extract of 100% bee propolis and undergoes strict quality control testing to guarantee that it is free from contaminants. Its antibacterial and immune-supporting properties provide a natural form of protection in our world of superbugs, increasing pollution, and compromised health.

How it works

Propolis contains high amounts of polyphenols – antioxidant compounds that include bioflavonoids. Bioflavonoids help guard against oxidative damage and have also been shown to support immune function in a variety of ways: they strengthen capillary walls and connective tissue, enhance vitamin C absorption, and offer support for upper respiratory tract health.

Some flavonoids found in propolis have also demonstrated an ability to inhibit inflammatory responses including reducing the production of pro-inflammatory nitrous oxide.

Propolis appears to support immune function in several ways, including stimulating phagocytosis, a process where white blood cells engulf and destroy bacteria. It also appears to activate dendritic cells involved in the early stages of the immune response. However, propolis does not destroy beneficial bacteria. Instead, it appears to target the undesirable bacteria, making it one of nature’s strongest antibiotic substances.

Propolis also contains trace minerals including magnesium, calcium, phosphorus, potassium, beta carotene, and vitamins B1 and B2.


Each Capsule Contains: 
Bee Propolis (bee hive of the honey bee Apis mellifera L.) 2:1 Extract  250mg
Purified to 100% Bee Propolis *Dry Herb Equivalent 500 mg

Non-medicinal ingredients: Microcrystalline cellulose, gelatin capsule (gelatin, purified water), silica, vegetable grade magnesium stearate (lubricant).

Additional information

Consult a health care practitioner if symptoms persist or worsen. Consult a health care practitioner prior to use if you are allergic to bee products, poplar tree products, or balsam of Peru, or if you are pregnant or breastfeeding. Hypersensitivity, such as allergy, has been known to occur, in which case discontinue use immediately. Keep out of the reach of children.


Research Although the precise mechanisms by which propolis soothes a sore throat and eases other cold symptoms remain unknown, research suggests that propolis possesses antimicrobial, antioxidant, and anti-ulcer activities. This is likely due to constituents of propolis including polyphenols, phenolic aldehydes, sequiterpene quinines, coumarins, and amino acids (Khalil, 2006).

Flavonoids isolated from propolis can markedly inhibit inflammatory responses, including suppressing the activation of nuclear factor kappa-beta (NF-kB), a pro-inflammatory molecule (FunakoshiTago et al., 2016). Propolis has also been seen to enhance immune system activity against fungal infection by modulating the expression of specific cell receptors in human large phagocytes (monocytes), a type of white blood cell (Búfalo et al., 2014). In the same study, propolis modulated production of tumour necrosis factor-alpha and interleukin-10, both of which are involved in immune system activity and inflammation.

In another laboratory study, researchers found that monocytes incubated with lipopolysaccharides and propolis caused an increase in activation of dendritic cells and had a bactericidal effect against Streptococcus mutans compared to cells incubated without propolis (Conti et al., 2016). Dendritic cells are essential for recognition and presentation of pathogens to T cells, meaning that propolis may help the immune system to identify and target invading microbes faster.

One of the earliest studies looking at the immune system benefits of propolis took place in an ear, nose and throat clinic in Poland in 1987 involving 50 adults infected with rhinovirus, which causes the common cold. The adults who took propolis recovered from their cold symptoms two and a half times faster than the control group not receiving propolis. Five patients recovered completely within just one day, sixteen recovered in two days, and three recovered in three days. In contrast, the placebo group took an average of almost five days (4.8 days) to recover (Szmeja et al., 1989).

Propolis toothpaste was found to support gum health and decrease plaque index scores in a study involving orthodontic appliances, suggesting a potential antibacterial and antioxidant effect with localized propolis use, such as in a spray (Machorowska-Pieniazek et al., 2016). When taken orally at a dose of 500 mg daily, propolis was found in one small pilot study to significantly reduce the occurrence of aphthous stomatitis (mouth ulcers) in adults, in addition to improving quality of life (Samet et al., 2007).

Compounds in propolis have demonstrated impressive antioxidant activity, including a capacity for scavenging free radicals and preventing lipid peroxidation (a process that results in cell damage) (Popova et al., 2015).